Mechanisms of Immunotoxicity: Stressors and Evaluators

The immune system defends the body against certain tumor cells and against foreign agents such as fungi, parasites, bacteria, and viruses. One of its main roles is to distinguish endogenous components from non-self-components. An unproperly functioning immune system is prone to primary immune defici...

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Veröffentlicht in:International journal of molecular sciences 2021-07, Vol.22 (15), p.8242
Hauptverfasser: Bou Zerdan, Maroun, Moussa, Sara, Atoui, Ali, Assi, Hazem I
Format: Artikel
Sprache:eng
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Zusammenfassung:The immune system defends the body against certain tumor cells and against foreign agents such as fungi, parasites, bacteria, and viruses. One of its main roles is to distinguish endogenous components from non-self-components. An unproperly functioning immune system is prone to primary immune deficiencies caused by either primary immune deficiencies such as genetic defects or secondary immune deficiencies such as physical, chemical, and in some instances, psychological stressors. In the manuscript, we will provide a brief overview of the immune system and immunotoxicology. We will also describe the biochemical mechanisms of immunotoxicants and how to evaluate immunotoxicity.
ISSN:1422-0067
1661-6596
1422-0067
DOI:10.3390/ijms22158242