Hypertension and Covid-19 vaccines: are there any differences between the different vaccines? A safety signal

Although no signal was found in clinical trials, a case series of stage III hypertension with mRNA CoV-2 vaccines (8 with tozinameran Pfizer, 1 with mRNA-1273 Moderna) was recently reported, suggesting that hypertension could be an adverse drug reaction (ADR) of Covid-19 vaccines. In order to valida...

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Veröffentlicht in:	European journal of clinical pharmacology 2021-12, Vol.77 (12), p.1937-1938
Hauptverfasser:	Bouhanick, Beatrice, Montastruc, François, Tessier, Samuel, Brusq, Clara, Bongard, Vanina, Senard, Jean-Michel, Montastruc, Jean-Louis, Herin, Fabrice
Format:	Artikel
Sprache:	eng
Schlagworte:	80 and over Adult Age Factors Aged Biomedical and Life Sciences Biomedicine Cardiology and cardiovascular system COVID-19 COVID-19 vaccines COVID-19 Vaccines / adverse effects Female Human health and pathology Humans Hypertension / etiology Letter to the Editor Life Sciences Male Middle Aged Pharmacology/Toxicology Sex Factors Vaccines
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Beschreibung
Zusammenfassung:	Although no signal was found in clinical trials, a case series of stage III hypertension with mRNA CoV-2 vaccines (8 with tozinameran Pfizer, 1 with mRNA-1273 Moderna) was recently reported, suggesting that hypertension could be an adverse drug reaction (ADR) of Covid-19 vaccines. In order to validate this signal, we investigated the data registered in VigiBase, the WHO pharmacovigilance database.
ISSN:	0031-6970 1432-1041
DOI:	10.1007/s00228-021-03197-8