A Case Report of Favourable Response of Polymyositis to Methotrexate Monotherapy

INTRODUCTION Steroids constitute either the main treatment for some rheumatic diseases such as temporal arteritis or may be used as a bridging therapy in others, such as rheumatoid arthritis.1,2 The efficacy of steroids in rheumatic diseases is well documented but there was always a concern regarding their well-known side effects. Initial laboratory workup revealed a CPK of 851u/L (normal up to 190u/l), a positive rheumatoid factor and antinuclear antibodies (1:320 speckled), positive anti-Ro, and normal thyroid function. Department of Rheumatology, Patras University Hospital, University of Patras Medical School, Patras, Greece 2.