Walking activity in a large cohort of boys with Duchenne muscular dystrophy

Introduction In this study we explored walking activity in a large cohort of boys with Duchenne muscular dystrophy (DMD). Methods Step activity (monitored for 7 days), functional ability, and strength were quantified in ambulatory boys (5‐12.9 years of age) with DMD and unaffected boys. Ambulatory s...

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Veröffentlicht in:Muscle & nerve 2021-02, Vol.63 (2), p.192-198
Hauptverfasser: Lott, Donovan J., Taivassalo, Tanja, Senesac, Claudia R., Willcocks, Rebecca J., Harrington, Ann M., Zilke, Kirsten, Cunkle, Hilary, Powers, Catherine, Finanger, Erika L., Rooney, William D., Tennekoon, Gihan I., Vandenborne, Krista
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Sprache:eng
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Zusammenfassung:Introduction In this study we explored walking activity in a large cohort of boys with Duchenne muscular dystrophy (DMD). Methods Step activity (monitored for 7 days), functional ability, and strength were quantified in ambulatory boys (5‐12.9 years of age) with DMD and unaffected boys. Ambulatory status was determined 2 years later. Results Two to 5 days of activity monitoring predicted weekly step activity (adjusted R2 = 0.80‐0.95). Age comparisons revealed significant declines for step activity with increasing age, and relationships were found between step activity with both function and strength (P 
ISSN:0148-639X
1097-4598
DOI:10.1002/mus.27119