The dynamic changes in the pattern of liver function tests in pregnant obese women

Obesity is an important problem in healthcare regarding gestating women. The objective of the present study was to highlight the impact that obesity has on the hepatic function in pregnant women by comparing the functional tests used in current practice. In addition, the aim was to identify possible...

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Veröffentlicht in:Experimental and therapeutic medicine 2021-09, Vol.22 (3), Article 986
Hauptverfasser: Teodorescu, Cristina Oana Daciana, Sandru, Florica, Charkaoui, Adham, Teodorescu, Andrei, Popa, Amorin Remus, Miron, Andreea-iuliana
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Sprache:eng
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Zusammenfassung:Obesity is an important problem in healthcare regarding gestating women. The objective of the present study was to highlight the impact that obesity has on the hepatic function in pregnant women by comparing the functional tests used in current practice. In addition, the aim was to identify possible predictors of liver damage by analyzing specific anthropometric data. The present study was descriptive, observational, retrospective, and based on the observation sheets found in the database of the Institute for the Health of the Mother and Child, the Obstetrics Gynecology Department of Polizu Hospital. Patients who presented for consultation in each trimester of pregnancy were included in the study. Demographic data taken into account included age, body mass index (BMI), provenance environment, anthropometric data: Abdominal circumference and the complete set of paraclinical data from which we extracted these specific liver tests: Aspartate aminotransferase (AST), alanine transferase (ALT), direct bilirubin (BD), serum albumin and gamma-glutamyl transferase (GGT). The present study included 157 patients divided into two groups, distributed as follows: Group A: 66 obese pregnant women (BMI >25 kg/[m.sup.2]) and group B: 91 patients with normal weight (BMI
ISSN:1792-0981
1792-1015
DOI:10.3892/etm.2021.10418