Acute Immune Thrombocytopenia (ITP) Following COVID-19 Vaccination in a Patient With Previously Stable ITP

Acute Immune Thrombocytopenia (ITP) Following COVID-19 Vaccination in a Patient With Previously Stable ITP

Abstract Immune thrombocytopenia (ITP) is an autoimmune condition associated with multiple risk factors including viral infections (hepatitis B virus/hepatitis C virus/cytomegalovirus, HIV, and recently severe acute respiratory syndrome coronavirus 2) and vaccines. Though immune mechanisms have been...

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Veröffentlicht in:Open Forum Infectious Diseases 2021-07, Vol.8 (7)
Hauptverfasser: Jawed, Muzamil, Khalid, Amna, Rubin, Mayer, Shafiq, Ramsha, Cemalovic, Nail
Format: Artikel
Sprache:eng
Schlagworte:
Autoimmunity
Complications and side effects
Coronaviruses
Novel ID Cases
Pharmaceutical industry
Risk factors
RNA
Severe acute respiratory syndrome
Thrombocytopenia
Vaccination
Virus diseases
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Zusammenfassung:Abstract Immune thrombocytopenia (ITP) is an autoimmune condition associated with multiple risk factors including viral infections (hepatitis B virus/hepatitis C virus/cytomegalovirus, HIV, and recently severe acute respiratory syndrome coronavirus 2) and vaccines. Though immune mechanisms have been proposed to explain the pathogenesis of acute ITP, autoimmunity with the coronavirus disease 2019 (COVID-19) vaccine is still unclear and needs further research. We report a case of acute ITP after administration of the Pfizer-BioNTech mRNA COVID-19 vaccine in a patient with previously stable ITP.
ISSN:2328-8957
2328-8957
DOI:10.1093/ofid/ofab343