Improvement in left ventricular ejection fraction after pharmacological up-titration in new-onset heart failure with reduced ejection fraction

Objective Recent studies have reported suboptimal up-titration of heart failure (HF) therapies in patients with heart failure and a reduced ejection fraction (HFrEF). Here, we report on the achieved doses after nurse-led up-titration, reasons for not achieving the target dose, subsequent changes in...

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Veröffentlicht in:Netherlands heart journal 2021-07, Vol.29 (7-8), p.383-393
Hauptverfasser: Nauta, J. F., Santema, B. T., van der Wal, M. H. L., Koops, A., Warink-Riemersma, J., van Dijk, K., Inkelaar, F., Prückl, S., Suwijn, J., van Deursen, V. M., Meijers, W. C., Coster, J., Westenbrink, B. D., de Boer, R. A., Hummel, Y., van Melle, J., van Veldhuisen, D. J., van der Meer, P., Voors, A. A.
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Sprache:eng
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Zusammenfassung:Objective Recent studies have reported suboptimal up-titration of heart failure (HF) therapies in patients with heart failure and a reduced ejection fraction (HFrEF). Here, we report on the achieved doses after nurse-led up-titration, reasons for not achieving the target dose, subsequent changes in left ventricular ejection fraction (LVEF), and mortality. Methods From 2012 to 2018, 378 HFrEF patients with a recent (
ISSN:1568-5888
1876-6250
DOI:10.1007/s12471-021-01591-6