Diabetic ketoacidosis drives COVID‐19 related hospitalizations in children with type 1 diabetes

Background Diabetes is a risk factor for poor COVID‐19 outcomes, but pediatric patients with type 1 diabetes are poorly represented in current studies. Methods T1D Exchange coordinated a US type 1 diabetes COVID‐19 registry. Forty‐six diabetes centers submitted pediatric cases for patients with labo...

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Veröffentlicht in:	Journal of diabetes 2021-08, Vol.13 (8), p.681-687
Hauptverfasser:	Alonso, Guy Todd, Ebekozien, Osagie, Gallagher, Mary Pat, Rompicherla, Saketh, Lyons, Sarah K., Choudhary, Abha, Majidi, Shideh, Pinnaro, Catherina T., Balachandar, Sadana, Gangat, Mariam, Curda Roberts, Alissa Jeanne, Marks, Brynn E., Creo, Ana, Sanchez, Janine, Seeherunvong, Tossaporn, Jimenez‐Vega, Jose, Patel, Neha S., Wood, Jamie R., Gabriel, Liana, Sumpter, Kathryn M., Wilkes, Meredith, Rapaport, Robert, Cymbaluk, Anna, Wong, Jenise C., Sanda, Srinath, Albanese‐O'neill, Anastasia
Format:	Artikel
Sprache:	eng
Schlagworte:	1型糖尿病 Adolescent Age Factors Biomarkers - blood Child Child, Preschool COVID-19 COVID-19 - complications COVID-19 - diagnosis COVID-19 - virology Cross-Sectional Studies Diabetes Diabetes Mellitus, Type 1 - blood Diabetes Mellitus, Type 1 - complications Diabetes Mellitus, Type 1 - diagnosis Diabetic ketoacidosis Diabetic Ketoacidosis - blood Diabetic Ketoacidosis - diagnosis Diabetic Ketoacidosis - etiology Disease Progression DKA Ethnicity Female Glucose Glucose monitoring Glycated Hemoglobin - metabolism Hospitalization Humans Infant Infant, Newborn Insulin Male Multisystem inflammatory syndrome in children Original pediatric Pediatrics Registries Risk Assessment Risk Factors type 1 diabetes United States Up-Regulation 新型冠状病毒肺炎
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Zusammenfassung:	Background Diabetes is a risk factor for poor COVID‐19 outcomes, but pediatric patients with type 1 diabetes are poorly represented in current studies. Methods T1D Exchange coordinated a US type 1 diabetes COVID‐19 registry. Forty‐six diabetes centers submitted pediatric cases for patients with laboratory confirmed COVID‐19. Associations between clinical factors and hospitalization were tested with Fisher's Exact Test. Logistic regression was used to calculate odds ratios for hospitalization. Results Data from 266 patients with previously established type 1 diabetes aged
ISSN:	1753-0393 1753-0407
DOI:	10.1111/1753-0407.13184