Multidimensional Prognostic Index (MPI) in elderly patients with acute myocardial infarction

Background Management of elderly patients with acute myocardial infarction (AMI) is challenging due to lack of knowledge about the link between fragility, outcomes and interventional procedures. Aims The aim of this study was to establish the prognostic role of the Multidimensional Prognostic Index...

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Veröffentlicht in:Aging clinical and experimental research 2021-07, Vol.33 (7), p.1875-1883
Hauptverfasser: Cammalleri, Valeria, Bonanni, Michela, Bueti, Francesca Maria, Matteucci, Andrea, Cammalleri, Lisa, Stifano, Giuseppe, Muscoli, Saverio, Romeo, Francesco
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Sprache:eng
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Zusammenfassung:Background Management of elderly patients with acute myocardial infarction (AMI) is challenging due to lack of knowledge about the link between fragility, outcomes and interventional procedures. Aims The aim of this study was to establish the prognostic role of the Multidimensional Prognostic Index (MPI) in elderly with AMI. Methods A total of 241 patients ≥ 65 years old with AMI were continuously enrolled in this prospective study and divided into three groups according to the MPI score. The primary endpoint was 30-day mortality. Secondary endpoints were 6-month mortality and rate of adverse events. Results In-hospital overall mortality rate was higher in MPI-3 ( p  = 0.009). Patients of MPI-3 had a significantly higher mortality rate regarding the primary endpoint with 30-day survival of 78.9%, compared to 97.4% and 97.2%, in MPI-1, MPI-2 ( p  
ISSN:1720-8319
1594-0667
1720-8319
DOI:10.1007/s40520-020-01718-6