Rapid glucose rise reduces heart rate variability in adults with type 1 diabetes: A prospective secondary outcome analysis

Rapid glucose rise reduces heart rate variability in adults with type 1 diabetes: A prospective secondary outcome analysis

To investigate differences in heart rate variability (HRV) during oral glucose tolerance tests (OGTTs) in response to the rate of change in glucose and to different glycaemic ranges in individuals with type 1 diabetes. This was a single‐centre, prospective, secondary outcome analysis in 17 individua...

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Veröffentlicht in:Diabetes, obesity & metabolism obesity & metabolism, 2021-07, Vol.23 (7), p.1681-1684
Hauptverfasser: Eckstein, Max L., Moser, Othmar, Tripolt, Norbert J., Pferschy, Peter N., Obermayer, Anna A. M., Kojzar, Harald, Mueller, Alexander, Abbas, Farah, Sourij, Caren, Sourij, Harald
Format: Artikel
Sprache:eng
Schlagworte:
autonomic regulation
Brief Report
Brief Reports
Diabetes
Diabetes mellitus (insulin dependent)
Glucose
Glucose tolerance
Heart rate
heart rate variability
Hemoglobin
oral glucose tolerance test
type 1 diabetes
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Zusammenfassung:To investigate differences in heart rate variability (HRV) during oral glucose tolerance tests (OGTTs) in response to the rate of change in glucose and to different glycaemic ranges in individuals with type 1 diabetes. This was a single‐centre, prospective, secondary outcome analysis in 17 individuals with type 1 diabetes (glycated haemoglobin 53 ± 6.3 mmol/L), who underwent two OGTTs (after 12 and 36 hours of fasting) investigating differences in HRV in response to rapid glucose increases/decreases and different glycaemic ranges during OGTT. Based on the rate of change in glucose level, the variables heart rate (P 50 ms difference (P 
ISSN:1462-8902
1463-1326
DOI:10.1111/dom.14287