Antibody Response Following a Two-Dose mRNA Vaccination Regimen, in Health Care Workers of a Tertiary Hospital in Athens, Greece

We analyzed the antibody responses of 564 hospital workers in Athens, Greece, after vaccination with two doses of the BNT162b2 (Comirnaty®; BioNTech and Pfizer) mRNA COVID-19 vaccine. A greater antibody increase was observed in women, younger age groups, previously infected individuals and personnel...

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Veröffentlicht in:	Journal of personalized medicine 2021-06, Vol.11 (6), p.576
Hauptverfasser:	Kontou, Elissavet, Ranellou, Kyriaki, Zoulas, Dimitrios, Bletsa, Anastasia, Rompola, Eirini, Piperaki, Evangelia-Theophano, Athanasiou, Nikolaos, Ampelakiotou, Kleio, Pratikaki, Maria, Stergiopoulou, Christina, Argyropoulou, Athina, Alevra, Androula, Megalou, Aggeliki, Tsirogianni, Alexandra
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antibody response Communication Coronaviruses COVID-19 COVID-19 vaccines Health care Hospitals Infections Medical personnel mRNA mRNA vaccines Population Precision medicine Serology Severe acute respiratory syndrome coronavirus 2 Vaccination Variance analysis
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Zusammenfassung:	We analyzed the antibody responses of 564 hospital workers in Athens, Greece, after vaccination with two doses of the BNT162b2 (Comirnaty®; BioNTech and Pfizer) mRNA COVID-19 vaccine. A greater antibody increase was observed in women, younger age groups, previously infected individuals and personnel working in COVID-19 clinics. Notably, individuals with a prior COVID-19 infection mounted a significantly higher antibody titer following the first dose than the rest of the population; the same was true for those working in COVID-19 clinics, even without history of previous infection.
ISSN:	2075-4426 2075-4426
DOI:	10.3390/jpm11060576