Side effects and antibody titer transition of the BNT162b2 messenger ribonucleic acid coronavirus disease 2019 vaccine in Japan

The coronavirus disease (COVID-19) has afflicted large populations worldwide. Although vaccines aroused great expectations, their side effects on Japanese people and the antibody titer transition after vaccination are unclear. The side effects of the BNT162b2 mRNA COVID-19 vaccine in participants wh...

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Veröffentlicht in:	Respiratory investigation 2021-09, Vol.59 (5), p.635-642
Hauptverfasser:	Izumo, Takehiro, Kuse, Naoyuki, Awano, Nobuyasu, Tone, Mari, Sakamoto, Keita, Takada, Kohei, Muto, Yutaka, Fujimoto, Kazushi, Saiki, Ayae, Ito, Yu, Matsumoto, Haruko, Inomata, Minoru
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibody titer BNT162 Vaccine Coronavirus disease COVID-19 COVID-19 Vaccines Female Humans IgG/IgM antibody Japan - epidemiology Male Original RNA, Messenger RNA, Viral SARS-CoV-2 Side effect Vaccine
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Zusammenfassung:	The coronavirus disease (COVID-19) has afflicted large populations worldwide. Although vaccines aroused great expectations, their side effects on Japanese people and the antibody titer transition after vaccination are unclear. The side effects of the BNT162b2 mRNA COVID-19 vaccine in participants who received vaccination at our center were investigated. Some participants were also surveyed for the antibody titer transition. In this study, 983 and 798 Japanese participants responded to the first and second doses, respectively. Side effects occurred in 757 (77.0%) and 715 participants (90.0%) after the first and second doses, respectively. No Grade 4 side effects occurred. The second dose had significantly more side effects than the first dose (p
ISSN:	2212-5345 2212-5353 2212-5353
DOI:	10.1016/j.resinv.2021.06.003