Correlation analysis of low-level serum uric acid and cardiovascular events in patients on peritoneal dialysis

Background The impact of serum uric acid (SUA) on development of cardiovascular disease (CVD) in patients undergoing peritoneal dialysis (PD) remains controversial, especially the impact of hypouricemia (HUA) on CVD. The aim of our study was to investigate the influence of low-level SUA on cardiovas...

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Veröffentlicht in:	International urology and nephrology 2021-11, Vol.53 (11), p.2399-2408
Hauptverfasser:	Li, Qiuyue, Wu, Cong, Kuang, Wenli, Zhan, Xiaojiang, Zhou, Jing
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Cardiovascular diseases Cardiovascular Diseases - blood Cardiovascular Diseases - etiology Cohort Studies Correlation analysis Correlation of Data Female Humans Male Medicine Medicine & Public Health Middle Aged Nephrology Nephrology - Original Paper Patients Peritoneal Dialysis Peritoneum Retrospective Studies Risk factors Uric acid Uric Acid - blood Urology
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Zusammenfassung:	Background The impact of serum uric acid (SUA) on development of cardiovascular disease (CVD) in patients undergoing peritoneal dialysis (PD) remains controversial, especially the impact of hypouricemia (HUA) on CVD. The aim of our study was to investigate the influence of low-level SUA on cardiovascular (CV) events in PD patients. Methods A retrospective cohort study was conducted.728 PD patients from February 1, 2010 to May 31, 2019 were enrolled. All demographic and laboratory data were collected at baseline and 6 months after PD treatment. The study cohort was divided into four groups according to SUA level (μmol/L) after 6 months of PD: Group1 (
ISSN:	0301-1623 1573-2584
DOI:	10.1007/s11255-021-02902-x