Evaluation of hematological parameters as an indicator of disease severity in Covid‐19 patients: Pakistan's experience

Background The severity of COVID‐19 could be evaluated by examining several blood parameters mainly white blood cell (WBC) count, granulocytes, platelet, and novel hemocytometric markers neutrophils to lymphocyte ratio (NLR), platelet‐to‐lymphocyte (PLR), and lymphocyte to monocyte ratio (LMR). The...

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Veröffentlicht in:Journal of clinical laboratory analysis 2021-06, Vol.35 (6), p.e23809-n/a
Hauptverfasser: Waris, Abdul, Din, Misbahud, Khalid, Atiqa, Abbas Lail, Raees, Shaheen, Asmat, Khan, Nida, Nawaz, Mehboob, Baset, Abdul, Ahmad, Imtiaz, Ali, Muhammad
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Sprache:eng
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Zusammenfassung:Background The severity of COVID‐19 could be evaluated by examining several blood parameters mainly white blood cell (WBC) count, granulocytes, platelet, and novel hemocytometric markers neutrophils to lymphocyte ratio (NLR), platelet‐to‐lymphocyte (PLR), and lymphocyte to monocyte ratio (LMR). The current study was conducted to investigate alteration in blood parameters and their association with the severity and mortality of COVID‐19 patients. Methodology An observational cross‐sectional study was conducted retrospectively, a total of 101 COVID‐19 positive patients were examined: 52 were mild, 24 were moderate, 09 were severe, and 16 were critically diseased patients. We also recorded 16 deaths associated with the critical group. The overall mean age observed in our study was 48.94 years, where the mean age for critical individuals was 62.12 ± 14.35 years. Results A significant association between the disease severity and elevation in blood parameters were observed. The WBC's and granulocyte count were significantly increased (p value
ISSN:0887-8013
1098-2825
1098-2825
DOI:10.1002/jcla.23809