Bothrops moojeni venom and its components - an overview

Belonging to the Viperidae family, are widely distributed in South America, tropical savanna ecoregion (Cerrado) of Argentina, Bolivia, Brazil, and Paraguay with medical importance in Brazil. Accidents caused by this species have a rapid local action with the development of tissue inflammation, caus...

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Veröffentlicht in:Journal of venom research 2021, Vol.11, p.26-33
Hauptverfasser: D'Amélio, Fernanda, Vigerelli, Hugo, de Brandão Prieto da Silva, Álvaro Rossan, Kerkis, Irina
Format: Artikel
Sprache:eng
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Zusammenfassung:Belonging to the Viperidae family, are widely distributed in South America, tropical savanna ecoregion (Cerrado) of Argentina, Bolivia, Brazil, and Paraguay with medical importance in Brazil. Accidents caused by this species have a rapid local action with the development of tissue inflammation, causing erythema, pain, and increased clotting time, which can culminate in gangrene or tissue necrosis. venom has a rich composition that remains underexplored, which is of utmost importance, both for elucidating the envenoming process and the vast library of new bioactive molecules kind of venom can offer. This review aims to analyze which components of the venom have already been characterized towards its structure and biological effect and highlight the pharmacological and biotechnological potential of this venom. Although snake venoms have been studied for their toxic effects for generations, innovative studies address their components as tools for discovering new therapeutic targets and new molecules with pharmacological and biotechnological potential.
ISSN:2044-0324
2044-0324