Reply to Krupenko et al. Comment on “Lee et al. The Combination of Loss of ALDH1L1 Function and Phenformin Treatment Decreases Tumor Growth in KRAS-Driven Lung Cancer Cancers 2020, 12, 1382”

Reply to Krupenko et al. Comment on “Lee et al. The Combination of Loss of ALDH1L1 Function and Phenformin Treatment Decreases Tumor Growth in KRAS-Driven Lung Cancer Cancers 2020, 12, 1382”

In the Cancers paper, we observed the increase ALDH1L1 protein expression following oncogenesis, as well as a therapeutic effect, by deleting the Aldh1l1 gene in KrasLA2 mice, a model of spontaneous non-small cell lung cancer (NSCLC) [...]

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Bibliographische Detailangaben
Veröffentlicht in:Cancers 2021-05, Vol.13 (9), p.2238
Hauptverfasser: Lee, Seon-Hyeong, Jeon, Yoon, Kang, Joon-Hee, Jang, Hyonchol, Hong, Kyeong-Man, Hong, Dongwan, Lee, Ho, Kim, Soo-Youl
Format: Artikel
Sprache:eng
Schlagworte:
Aldehyde dehydrogenase
Antibodies
Bioinformatics
Dehydrogenases
Gene expression
Genomes
Informatics
Isoforms
Isotypes
K-Ras protein
Lung cancer
Mutation
Non-small cell lung carcinoma
Peptides
Protein expression
Proteins
Reply
Small cell lung carcinoma
Tumorigenesis
Western blotting
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Zusammenfassung:In the Cancers paper, we observed the increase ALDH1L1 protein expression following oncogenesis, as well as a therapeutic effect, by deleting the Aldh1l1 gene in KrasLA2 mice, a model of spontaneous non-small cell lung cancer (NSCLC) [...]
ISSN:2072-6694
2072-6694
DOI:10.3390/cancers13092238