Dietary Blueberry and Soluble Fiber Supplementation Reduces Risk of Gestational Diabetes in Women with Obesity in a Randomized Controlled Trial

Gestational diabetes mellitus (GDM) is a growing public health concern and maternal obesity and poor dietary intakes could be implicated. Dietary polyphenols and fiber mitigate the risk of diabetes and its complications, but little is known about their efficacy in preventing GDM. We examined the eff...

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Veröffentlicht in:	The Journal of nutrition 2021-05, Vol.151 (5), p.1128-1138
Hauptverfasser:	Basu, Arpita, Feng, Du, Planinic, Petar, Ebersole, Jeffrey L, Lyons, Timothy J, Alexander, James M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biomarkers - blood Birth weight Blood Glucose Blood pressure Blueberries Blueberry Plants Body weight gain C-reactive protein Cholesterol Complications Diabetes Diabetes mellitus Diabetes, Gestational - prevention & control Diet Dietary Fiber - administration & dosage Dietary supplements Female Food intake Fruits Gestation Gestational diabetes gestational weight gain Glucose Glycated Hemoglobin - metabolism Health risks High density lipoprotein Humans Inflammation - blood Inflammation - metabolism Insulin Lipids Lipids - blood Low density lipoprotein Nutrition Nutrition and Disease Obesity Obesity, Maternal - complications Obesity, Maternal - diet therapy Polyphenols Pregnancy Prenatal Nutritional Physiological Phenomena Public health Risk soluble fiber Triglycerides Variance analysis Women Womens health Young Adult
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Zusammenfassung:	Gestational diabetes mellitus (GDM) is a growing public health concern and maternal obesity and poor dietary intakes could be implicated. Dietary polyphenols and fiber mitigate the risk of diabetes and its complications, but little is known about their efficacy in preventing GDM. We examined the effects of whole blueberry and soluble fiber supplementation on primary outcomes of cardiometabolic profiles in women at high risk of developing GDM. Women (n = 34; mean ± SD age: 27 ± 5 y; BMI: 35.5 ± 4.0 kg/m2; previous history of GDM ∼56%; Hispanic ∼79%) were recruited in early pregnancy (
ISSN:	0022-3166 1541-6100
DOI:	10.1093/jn/nxaa435