Applying prospective genomic surveillance to support investigation of hospital-onset COVID-19

Applying prospective genomic surveillance to support investigation of hospital-onset COVID-19

[...]changes in SARS-CoV-2 diagnostic methods resulted in technical difficulties in obtaining sufficient good-quality genetic material for sequencing. [...]the speed from sampling to sequencing to analysis is crucial; for maximum impact, genomic data should be available to inform real-time decision-...

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Veröffentlicht in:The Lancet infectious diseases 2021-07, Vol.21 (7), p.916-917
Hauptverfasser: Hamilton, William L, Fieldman, Tom, Jahun, Aminu, Warne, Ben, Illingworth, Christopher J R, Jackson, Chris, Blane, Beth, Moore, Elinor, Weekes, Michael P, Peacock, Sharon J, De Angelis, Daniela, Goodfellow, Ian, Gouliouris, Theodore, Török, M Estée, Curran, Martin D, Parmar, Surendra, Hosmillo, Myra, Chaudhry, Yasmin, Pinckert, Malte L, Georgana, Iliana, Izuagbe, Rhys, Ferris, Mark, Workman, Chris, Jones, Nick K, Rivett, Lucy, Sparkes, Dominic, Routledge, Matthew, Enoch, David, Whitehorn, James, Moody, Christine, Brennan, Liam, Smith, Richard, Tsui, Rachel, Bousfield, Rachel, Pocock, Joanna, Toleman, Michelle, Payne, Helen, Coscione, Suny, Myers, Chloe, Sharrocks, Katherine, Ravji, Pooja, Leong, Clare, Ramsay, Isobel
Format: Artikel
Sprache:eng
Schlagworte:
Coronaviruses
Correspondence
COVID-19
Decision making
Disease transmission
Gene sequencing
Genomes
Genomics
Hospitals
Human resources
Humans
Infectious diseases
Nosocomial infections
Prospective Studies
SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2
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Zusammenfassung:[...]changes in SARS-CoV-2 diagnostic methods resulted in technical difficulties in obtaining sufficient good-quality genetic material for sequencing. [...]the speed from sampling to sequencing to analysis is crucial; for maximum impact, genomic data should be available to inform real-time decision-making. [...]sustained funding and human resource capacity are essential for consistent service delivery.
ISSN:1473-3099
1474-4457
1474-4457
DOI:10.1016/S1473-3099(21)00251-6