TRTools: a toolkit for genome-wide analysis of tandem repeats

Abstract Summary A rich set of tools have recently been developed for performing genome-wide genotyping of tandem repeats (TRs). However, standardized tools for downstream analysis of these results are lacking. To facilitate TR analysis applications, we present TRTools, a Python library and suite of...

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Veröffentlicht in:Bioinformatics 2021-05, Vol.37 (5), p.731-733
Hauptverfasser: Mousavi, Nima, Margoliash, Jonathan, Pusarla, Neha, Saini, Shubham, Yanicky, Richard, Gymrek, Melissa
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Sprache:eng
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Zusammenfassung:Abstract Summary A rich set of tools have recently been developed for performing genome-wide genotyping of tandem repeats (TRs). However, standardized tools for downstream analysis of these results are lacking. To facilitate TR analysis applications, we present TRTools, a Python library and suite of command line tools for filtering, merging and quality control of TR genotype files. TRTools utilizes an internal harmonization module, making it compatible with outputs from a wide range of TR genotypers. Availability and implementation TRTools is freely available at https://github.com/gymreklab/TRTools. Detailed documentation is available at https://trtools.readthedocs.io. Supplementary information Supplementary data are available at Bioinformatics online.
ISSN:1367-4803
1367-4811
1460-2059
1367-4811
DOI:10.1093/bioinformatics/btaa736