CDX2 regulates ACE expression in blood development and leukemia cells
•Expression of caudal-related homeobox gene 2 (CDX2) and angiotensin-converting enzyme (ACE) correlates during hematopoietic emergence.•This emergence occurs in human and mouse embryos and in human acute myeloid leukemia; CDX2 homeoprotein also binds to the ACE promoter.
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| Veröffentlicht in: | Blood advances 2021-04, Vol.5 (7), p.2012-2016 |
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| container_end_page | 2016 |
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| container_issue | 7 |
| container_start_page | 2012 |
| container_title | Blood advances |
| container_volume | 5 |
| creator | El Omar, Reine Julien, Emmanuelle Biasch, Katia Guffroy, Blandine Lioure, Bruno Vallat, Laurent Gross, Isabelle Domon-Dell, Claire Lanza, François Gachet, Christian Negroni, Matteo Freund, Jean-Noël Tavian, Manuela |
| description | •Expression of caudal-related homeobox gene 2 (CDX2) and angiotensin-converting enzyme (ACE) correlates during hematopoietic emergence.•This emergence occurs in human and mouse embryos and in human acute myeloid leukemia; CDX2 homeoprotein also binds to the ACE promoter. |
| doi_str_mv | 10.1182/bloodadvances.2020003563 |
| format | Article |
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| source | DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Life Sciences Stimulus Report |
| title | CDX2 regulates ACE expression in blood development and leukemia cells |
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