Choroidal thickness is associated with renal hemodynamics in essential hypertension

The choroid is the most vascularized structure of the eye and plays a central role in the development of the retinal vascular changes that occur in arterial hypertension. Changes of choroidal thickness (ChT) assessed by optical coherence tomography (OCT) technology could reflect the vascular complic...

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Veröffentlicht in:The journal of clinical hypertension (Greenwich, Conn.) Conn.), 2020-02, Vol.22 (2), p.245-253
Hauptverfasser: Geraci, Giulio, Maria Zammuto, Marta, Vadalà, Maria, Mattina, Alessandro, Castellucci, Massimo, Guarrasi, Giulia, Nardi, Emilio, Maida, Carlo, Zanoli, Luca, Cillino, Salvatore, Cottone, Santina, Mulè, Giuseppe
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Sprache:eng
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Zusammenfassung:The choroid is the most vascularized structure of the eye and plays a central role in the development of the retinal vascular changes that occur in arterial hypertension. Changes of choroidal thickness (ChT) assessed by optical coherence tomography (OCT) technology could reflect the vascular complications of hypertension. Also, intrarenal hemodynamic damage, associated with endothelial dysfunction, demonstrated to be a good indicator of systemic morphofunctional arterial impairment. The aim of this study is to assess the relationship between ChT and renal hemodynamics in subjects with essential hypertension. Routine laboratory tests, clinical history, and physical examination, including blood pressure assessment, were performed in 90 subjects with essential hypertension. All patients underwent Doppler ultrasonographic evaluation of intra‐renal hemodynamics and OCT imaging to assess ChT. When subjects were divided in two groups based on renal resistive index (RRI), group I (RRI ≥ 75% percentile) showed significantly lower values of ChT than group II (RRI 
ISSN:1524-6175
1751-7176
DOI:10.1111/jch.13777