Anterior uveitis in paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2

Blood tests showed a high C-reactive protein (289 mg/L), elevated liver enzymes—aspartate aminotransferase was 186 U/L, and alanine aminotransferase was 123 U/L—elevated troponin (78 ng/L), elevated N-terminal-pro-B-type natriuretic peptide (6302 pg/mL), elevated ferritin (1991 μg/L), low albumin (19·9 g/L), and a coagulopathy—prothrombin time 18·1, activated partial thromboplastin time 42, fibrinogen 6·1 g/L, and D-dimer 41 mg/L. The time course of the presenting symptoms in our patient strongly suggests an association between SARS-CoV-2 infection and AU—although other possible causes of uveitis cannot completely be excluded due to the absence of additional screening tests. Recognition and treatment of AU is important due to the possible ocular complications—including posterior synechiae, band keratopathy, a rise in intraocular pressure leading to glaucoma, cataract, and cystoid macular oedema—potentially leading to permanent visual impairment (video).