AT-CuAAC Synthesis of Mechanically Interlocked Oligonucleotides
We present a simple strategy for the synthesis of main chain oligonucleotide rotaxanes with precise control over the position of the macrocycle. The novel DNA-based rotaxanes were analyzed to assess the effect of the mechanical bond on their properties.
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Veröffentlicht in: | Journal of the American Chemical Society 2020-04, Vol.142 (13), p.5985-5990 |
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Hauptverfasser: | , , , , , , , |
Format: | Artikel |
Sprache: | eng |
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Online-Zugang: | Volltext |
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Zusammenfassung: | We present a simple strategy for the synthesis of main chain oligonucleotide rotaxanes with precise control over the position of the macrocycle. The novel DNA-based rotaxanes were analyzed to assess the effect of the mechanical bond on their properties. |
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ISSN: | 0002-7863 1520-5126 |
DOI: | 10.1021/jacs.0c01670 |