The association of viral load and disease severity in children with COVID‐19

It is still not fully understood how to predict the future prognosis of patients at the diagnosis coronavirus disease 2019 (COVID‐19) due to the wide clinical range of the disease. We aimed to evaluate whether severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) viral load could predict the...

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Veröffentlicht in:Journal of medical virology 2021-05, Vol.93 (5), p.3077-3083
Hauptverfasser: Aykac, Kubra, Cura Yayla, Burcu Ceylan, Ozsurekci, Yasemin, Evren, Kubra, Oygar, Pembe Derin, Gurlevik, Sibel Lacinel, Coskun, Tugce, Tasci, Onur, Demirel Kaya, Filiz, Fidanci, Ilknur, Tasar, Medine Aysin, Alp, Alpaslan, Cengiz, Ali Bulent, Karahan, Sevilay, Ceyhan, Mehmet
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Sprache:eng
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Zusammenfassung:It is still not fully understood how to predict the future prognosis of patients at the diagnosis coronavirus disease 2019 (COVID‐19) due to the wide clinical range of the disease. We aimed to evaluate whether severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) viral load could predict the clinical course of pediatric patients. This study was conducted retrospectively with medical records of pediatric patients who were tested for SARS‐CoV2 between April 12 and October 25, 2020 in the University of Health Sciences, Ankara Educating and Training Hospital and Hacettepe University Faculty of Medicine. We evaluated 518 pediatric patients diagnosed with COVID‐19 and classified according to severity as asymptomatic (16.2%), mild (59.6%), moderate (20.2%), and critical/severe (3.9%) cases. We analyzed patients in four groups in terms of ages:
ISSN:0146-6615
1096-9071
DOI:10.1002/jmv.26853