The Outcome of Acute Lymphoblastic Leukemia in 109 Adult Iraqi Patients

While many studies addressed the outcome of adult ALL in developed Western countries, there is paucity of such prospective studies from developing Mediterranean ones. This is a prospective cohort study conducted at Hiwa Cancer Hospital in Sulaimani city and Nanakali Hospital in Erbil city-Kurdistan...

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Veröffentlicht in:	Indian journal of hematology & blood transfusion 2021-04, Vol.37 (2), p.264-270
Hauptverfasser:	Mohammed, Dyna Jaza, Jalal, Sana Dlawar, Yassin, Ahmed Khudair, Mohammed, Ali Ibrahim, Al-Allawi, Nasir Abdulsalam
Format:	Artikel
Sprache:	eng
Schlagworte:	Adults Blood Transfusion Medicine Clinical outcomes Epidemiology Hematology Human Genetics Leukemia Medicine Medicine & Public Health Oncology Original Original Article
Online-Zugang:	Volltext
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Zusammenfassung:	While many studies addressed the outcome of adult ALL in developed Western countries, there is paucity of such prospective studies from developing Mediterranean ones. This is a prospective cohort study conducted at Hiwa Cancer Hospital in Sulaimani city and Nanakali Hospital in Erbil city-Kurdistan Iraq from March 2012 to August 2017. The main characteristics of adult ALL patients, type of therapy and risk factors were analyzed to assess their impact on treatment outcome and survival status. A total of 109 adult ALL patients were included with a median age of 24 years and male to female ratio of 1.7:1. B-ALL accounted for 76.1% of the cases, while the rest were T-ALL. BCR-ABL rearrangement was encountered in 12% of B-ALL. Complete remission (CR) rate was 81.7%, the overall 5 year survival (OS) was 38%, Relapse Free 5 year Survival (RFS) was 49%. Younger adults (
ISSN:	0971-4502 0974-0449 0974-0449 0971-4502
DOI:	10.1007/s12288-020-01345-1