Loop Diuretics in Severe Bronchopulmonary Dysplasia: Cumulative Use and Associations with Mortality and Age at Discharge

To measure between-center variation in loop diuretic use in infants developing severe bronchopulmonary dysplasia (BPD) in US children's hospitals, and to compare mortality and age at discharge between infants from low-use centers and infants from high-use centers. We performed a retrospective c...

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Veröffentlicht in:	The Journal of pediatrics 2021-04, Vol.231, p.43-49.e3
Hauptverfasser:	Bamat, Nicolas A., Nelin, Timothy D., Eichenwald, Eric C., Kirpalani, Haresh, Laughon, Matthew M., Jackson, Wesley M., Jensen, Erik A., Gibbs, Kathleen A., Lorch, Scott A.
Format:	Artikel
Sprache:	eng
Schlagworte:	artificial respiration bronchopulmonary dysplasia Bronchopulmonary Dysplasia - diagnosis Bronchopulmonary Dysplasia - drug therapy Bronchopulmonary Dysplasia - mortality diuretics Drug Administration Schedule Female Healthcare Disparities - statistics & numerical data Hospitals, Pediatric Humans Infant Infant, Newborn Infant, Premature Linear Models Logistic Models Male medication therapy management Multivariate Analysis Patient Discharge - statistics & numerical data Practice Patterns, Physicians' - statistics & numerical data premature infant Retrospective Studies Severity of Illness Index Sodium Potassium Chloride Symporter Inhibitors - therapeutic use Treatment Outcome United States
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Zusammenfassung:	To measure between-center variation in loop diuretic use in infants developing severe bronchopulmonary dysplasia (BPD) in US children's hospitals, and to compare mortality and age at discharge between infants from low-use centers and infants from high-use centers. We performed a retrospective cohort study of preterm infants at
ISSN:	0022-3476 1097-6833
DOI:	10.1016/j.jpeds.2020.10.073