A Rare Case of Primary Signet-Ring Cell Cervical Carcinoma: Early Stage with Independent Bilateral Ovarian Metastases

Primary signet-ring cell carcinoma of the uterine cervix (PSRCCC) is defined as a mucinous carcinoma. PSRCCC with independent bilateral ovarian metastases has not been previously reported in the literature. Herein we describe a case of PSRCCC with ovarian involvement. The patient underwent a detaile...

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Veröffentlicht in:OncoTargets and therapy 2021-01, Vol.14, p.2101-2107
Hauptverfasser: Li, Shiyun, Gan, Fuqiang, Luo, Manling, Luo, Puying
Format: Artikel
Sprache:eng
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Zusammenfassung:Primary signet-ring cell carcinoma of the uterine cervix (PSRCCC) is defined as a mucinous carcinoma. PSRCCC with independent bilateral ovarian metastases has not been previously reported in the literature. Herein we describe a case of PSRCCC with ovarian involvement. The patient underwent a detailed complete physical examination, and surgery was then performed to resect all of the tumors. All tumors expressed human papillomavirus 18 no distant tumors were detected, and estrogen receptor and progesterone receptor testing were negative, suggesting that the cervix was the primary site. This is the first report of a case of PSRCCC metastasis to bilateral ovaries only. Conservative management of human papillomavirus-associated type endocervical adenocarcinomas with independent ovarian metastases should be considered.
ISSN:1178-6930
1178-6930
DOI:10.2147/OTT.S300424