A Diffusion Longitudinal MR Imaging Study in Normal-Appearing White Matter in Untreated Relapsing-Remitting Multiple Sclerosis

Our aim was to evaluate the hypothesis that water diffusion alterations are present in normal-appearing white matter of patients with relapsing-remitting multiple sclerosis (RRMS) and to assess their change with time. Fifty-four subjects with clinically diagnosed RRMS, with disease duration of less...

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Veröffentlicht in:	American Journal of Neuroradiology 2007-03, Vol.28 (3), p.475-478
Hauptverfasser:	Garaci, F.G, Colangelo, V, Ludovici, A, Gaudiello, F, Marziali, S, Centonze, D, Boffa, L, Simonetti, G, Floris, R
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Biological and medical sciences Brain Brain - pathology Diffusion Magnetic Resonance Imaging Disability Evaluation Fundamental and applied biological sciences. Psychology Human Humans Investigative techniques, diagnostic techniques (general aspects) Learning. Memory Longitudinal Studies Medical sciences Memory Middle Aged Multimodal perception Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis Multiple Sclerosis, Relapsing-Remitting - pathology Nerve Fibers, Myelinated - pathology Nervous system Neurology Perception Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Radiodiagnosis. Nmr imagery. Nmr spectrometry Recurrence
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Zusammenfassung:	Our aim was to evaluate the hypothesis that water diffusion alterations are present in normal-appearing white matter of patients with relapsing-remitting multiple sclerosis (RRMS) and to assess their change with time. Fifty-four subjects with clinically diagnosed RRMS, with disease duration of less than 12 months and an expanded disability status scale (EDSS) score of
ISSN:	0195-6108 1936-959X 1432-1920