Aging delay: of mice and men
The evaluation of the safety of a drug in rodents that may be used as geroprotectors is a challenge of current times. In the paper, we discuss approaches to long-term assays for selection of potent aging delay drugs for humans. Priority is given to methods combining evaluation of carcinogenic safety...
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| Veröffentlicht in: | Acta bio-medica : Atenei Parmensis 2021-01, Vol.92 (1), p.e2021073 |
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| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | The evaluation of the safety of a drug in rodents that may be used as geroprotectors is a challenge of current times. In the paper, we discuss approaches to long-term assays for selection of potent aging delay drugs for humans. Priority is given to methods combining evaluation of carcinogenic safety and life-spanning potential. The use of such methods will be time-efficient and economically feasible. |
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| ISSN: | 0392-4203 2531-6745 |
| DOI: | 10.23750/abm.v92i1.11273 |