Changes in Seizure Frequency and Antiepileptic Therapy during Pregnancy

In a prospective study involving women with epilepsy, the incidence of seizures was similar regardless of whether women were pregnant or not pregnant during similar time periods. Pregnant women had more changes in the dose of anticonvulsant drugs during pregnancy than did nonpregnant women.

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Bibliographische Detailangaben
Veröffentlicht in:	The New England journal of medicine 2020-12, Vol.383 (26), p.2547-2556
Hauptverfasser:	Pennell, Page B, French, Jacqueline A, May, Ryan C, Gerard, Elizabeth, Kalayjian, Laura, Penovich, Patricia, Gedzelman, Evan, Cavitt, Jennifer, Hwang, Sean, Pack, Alison M, Sam, Maria, Miller, John W, Wilson, Steffanie H, Brown, Carrie, Birnbaum, Angela K, Meador, Kimford J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anticonvulsants - administration & dosage Antiepileptic agents Childbirth & labor Confidence intervals Convulsions & seizures Diaries Drug dosages Epilepsy Epilepsy - drug therapy Female Fetuses Humans Incidence Postpartum Postpartum Period Pregnancy Pregnancy Complications - drug therapy Prospective Studies Risk factors Seizures Seizures - epidemiology Seizures - prevention & control Womens health
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Beschreibung
Zusammenfassung:	In a prospective study involving women with epilepsy, the incidence of seizures was similar regardless of whether women were pregnant or not pregnant during similar time periods. Pregnant women had more changes in the dose of anticonvulsant drugs during pregnancy than did nonpregnant women.
ISSN:	0028-4793 1533-4406
DOI:	10.1056/NEJMoa2008663