CovMT: an interactive SARS-CoV-2 mutation tracker, with a focus on critical variants

CovMT, which is updated daily, summarises mutations from more than 450 000 isolates into groups of generic virus clades, lineages, and more specific mutation sets we call mutation fingerprints. Nonsynonymous mutations in the RBD region have a high potential to be linked to increased binding efficiency, increased infectivity, and the potential to evade antibodies.2–4 To track all similar variants, we ranked mutations in the RBD region based on their appearance in the number of isolate genomes in CovMT. With a particular focus on critical mutations in the RBD region of the spike protein, and with an option to seamlessly accrue the clinical metadata, including disease severity, we believe that CovMT will be useful for scientists, the general public, and authorities to explore country-specific information.