Synthesis, anticancer and antimicrobial evaluation of new benzofuran based derivatives: PI3K inhibition, quorum sensing and molecular modeling study

Synthesis, anticancer and antimicrobial evaluation of new benzofuran based derivatives: PI3K inhibition, quorum sensing and molecular modeling study

[Display omitted] •Compounds 8, 9 and 11 were the most active anticancer with IC50 

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Veröffentlicht in:Bioorganic & medicinal chemistry 2021-02, Vol.31, p.115976-115976, Article 115976
Hauptverfasser: El-Khouly, Omar A., Henen, Morkos A., El-Sayed, Magda A.-A., Shabaan, Mona I., El-Messery, Shahenda M.
Format: Artikel
Sprache:eng
Schlagworte:
Anticancer
Antimicrobial
Benzofuran
Hybridization
Molecular modeling
NOESY
PI3K
Quorum sensing
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Zusammenfassung:[Display omitted] •Compounds 8, 9 and 11 were the most active anticancer with IC50 
ISSN:0968-0896
1464-3391
DOI:10.1016/j.bmc.2020.115976