Anti-hypercholesterolemic potential of diet supplemented with Anchomanes difformis and Pleurotus tuberregium tubers in high cholesterol fed rats

Background One significant ethnomedicinal motivation behind Pleurotus tuberregium (PTT) and Anchomanes difformis (ADT) tubers is cardiovascular-related conditions treatment. This investigation is in this way planned for deciding the impact of PTT and ADT enhanced eating routine on key enzymes linked...

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Veröffentlicht in:Journal of diabetes and metabolic disorders 2020-12, Vol.19 (2), p.1139-1155
Hauptverfasser: Oyetayo, Folake Lucy, Akomolafe, Seun Funmilola, Ogundumi, Oluwatosin Adesola
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Sprache:eng
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Zusammenfassung:Background One significant ethnomedicinal motivation behind Pleurotus tuberregium (PTT) and Anchomanes difformis (ADT) tubers is cardiovascular-related conditions treatment. This investigation is in this way planned for deciding the impact of PTT and ADT enhanced eating routine on key enzymes linked with hypercholesterolemia in elevated cholesterol fed rodents. Methods Rats were isolated into control group, hypercholesterolemic-prompted untreated group, hypercholesterolemic-treated groups with dietary routine containing PTT (5% and 10%), ADT (5% and 10%), 5% PTT and 5% ADT conbination and traditional medication, atorvastatin for 28 days. Ten rodents were utilized for every one of the groups. Results Feeding with PTT and ADT comprehensive eating regimen and their combination significantly (P 
ISSN:2251-6581
2251-6581
DOI:10.1007/s40200-020-00615-z