Short or Long Sleep Duration and CKD: A Mendelian Randomization Study

Short or Long Sleep Duration and CKD: A Mendelian Randomization Study

Studies have found sleeping behaviors, such as sleep duration, to be associated with kidney function and cardiovascular disease risk. However, whether short or long sleep duration is a causative factor for kidney function impairment has been rarely studied. We studied data from participants aged 40-...

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Veröffentlicht in:Journal of the American Society of Nephrology 2020-12, Vol.31 (12), p.2937-2947
Hauptverfasser: Park, Sehoon, Lee, Soojin, Kim, Yaerim, Lee, Yeonhee, Kang, Min Woo, Kim, Kwangsoo, Kim, Yong Chul, Han, Seung Seok, Lee, Hajeong, Lee, Jung Pyo, Joo, Kwon Wook, Lim, Chun Soo, Kim, Yon Su, Kim, Dong Ki
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Aged
Clinical Research
Cohort Studies
Female
Humans
Logistic Models
Male
Mendelian Randomization Analysis
Middle Aged
Odds Ratio
Prevalence
Renal Insufficiency, Chronic - diagnosis
Renal Insufficiency, Chronic - epidemiology
Sleep
Time Factors
United Kingdom
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Zusammenfassung:Studies have found sleeping behaviors, such as sleep duration, to be associated with kidney function and cardiovascular disease risk. However, whether short or long sleep duration is a causative factor for kidney function impairment has been rarely studied. We studied data from participants aged 40-69 years in the UK Biobank prospective cohort, including 25,605 self-reporting short-duration sleep (
ISSN:1046-6673
1533-3450
DOI:10.1681/ASN.2020050666