Isolation of diverse bioactive compounds from Euphorbia balsamifera: Cytotoxicity and antibacterial activity studies

Isolation of diverse bioactive compounds from Euphorbia balsamifera: Cytotoxicity and antibacterial activity studies

Antibacterial and cytotoxic activities ofEuphorbia balsamifera, fractions and pure compounds were evaluated.The cytotoxic assays forHCT116, HePG2 and MCF7 showed a significant IC50: 54.7 and 76.2 µg/mL of non-polar fraction “n-hexane” against HCT116 and HePG2, respectively. Antibacterial results rev...

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Veröffentlicht in:Saudi journal of biological sciences 2021-01, Vol.28 (1), p.417-426
Hauptverfasser: Aljubiri, Salha M, Mahgoub, Samir A., Almansour, Abdulrahman I., Shaaban, Mohamed, Shaker, Kamel H.
Format: Artikel
Sprache:eng
Schlagworte:
Antibacterial
Asir region
Cytotoxicity
Euphorbia balsamifera
GC–MS
Isolation
Original
Spectroscopy
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Zusammenfassung:Antibacterial and cytotoxic activities ofEuphorbia balsamifera, fractions and pure compounds were evaluated.The cytotoxic assays forHCT116, HePG2 and MCF7 showed a significant IC50: 54.7 and 76.2 µg/mL of non-polar fraction “n-hexane” against HCT116 and HePG2, respectively. Antibacterial results revealed that plant fractions exhibited significant potential against the tested pathogens than the total extract where n-butanol and ethyl acetate fractions showed significant antibacterial activity (P 
ISSN:1319-562X
2213-7106
DOI:10.1016/j.sjbs.2020.10.025