Melanoma central nervous system metastases: An update to approaches, challenges, and opportunities

Melanoma central nervous system metastases: An update to approaches, challenges, and opportunities

In February 2018, the Melanoma Research Foundation and the Moffitt Cancer Center hosted the Second Summit on Melanoma Central Nervous System (CNS) Metastases in Tampa, Florida. In this white paper, we outline the current status of basic science, translational, and clinical research into melanoma bra...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Pigment cell and melanoma research 2019-05, Vol.32 (3), p.458-469
Hauptverfasser: Eroglu, Zeynep, Holmen, Sheri L., Chen, Qing, Khushalani, Nikhil I., Amaravadi, Ravi, Thomas, Reena, Ahmed, Kamran A., Tawbi, Hussein, Chandra, Sunandana, Markowitz, Joseph, Smalley, Inna, Liu, James K. C., Chen, Yian Ann, Najjar, Yana G., Karreth, Florian A., Abate‐Daga, Daniel, Glitza, Isabella C., Sosman, Jeffrey A., Sondak, Vernon K., Bosenberg, Marcus, Herlyn, Meenhard, Atkins, Michael B., Kluger, Harriet, Margolin, Kim, Forsyth, Peter A., Davies, Michael A., Smalley, Keiran S. M.
Format: Artikel
Sprache:eng
Schlagworte:
Brain
Brain cancer
brain metastases
Cancer
Central nervous system
Central Nervous System Neoplasms - secondary
Central Nervous System Neoplasms - therapy
Disease Management
Humans
Immunotherapy
Melanoma
Melanoma - pathology
Melanoma - therapy
Metastases
Metastasis
Molecular Targeted Therapy
Nervous system
targeted therapy
Upgrading
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:In February 2018, the Melanoma Research Foundation and the Moffitt Cancer Center hosted the Second Summit on Melanoma Central Nervous System (CNS) Metastases in Tampa, Florida. In this white paper, we outline the current status of basic science, translational, and clinical research into melanoma brain metastasis development and therapeutic management. We further outline the important challenges that remain for the field and the critical barriers that need to be overcome for continued progress to be made in this clinically difficult area.
ISSN:1755-1471
1755-148X
DOI:10.1111/pcmr.12771