Evaluation of DWI and ADC Sequences' Diagnostic Values in Benign and Malignant Pulmonary Lesions

The gold standard for the diagnosis of lung cancer is conducting a histopathologic study. It is also diagnosed based on some features of a computed tomography (CT) scan. Imposed radiation is a prominent side effect of a CT scan. Diffusion-weighted imaging (DWI) apparent diffusion coefficient (ADC) i...

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Veröffentlicht in:Turkish Thoracic Journal 2020-11, Vol.21 (6), p.390-396
Hauptverfasser: Mahdavi Rashed, Masoud, Nekooei, Sirous, Nouri, Marzieh, Borji, Nahid, Khadembashi, Alireza
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Sprache:eng
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Zusammenfassung:The gold standard for the diagnosis of lung cancer is conducting a histopathologic study. It is also diagnosed based on some features of a computed tomography (CT) scan. Imposed radiation is a prominent side effect of a CT scan. Diffusion-weighted imaging (DWI) apparent diffusion coefficient (ADC) images have currently been used in the diagnosis of different lesions, including those of the brain and breast, and their uses in lung lesions are being evaluated. In this study, to find a safe, sensitive, and specific method, we aimed to assess DWI imaging to replace the CT scan and the positron emission tomography scan. A total of 29 patients were enrolled in the study. In b800 images in DWI, spinal cord and lesion signals were measured, and the lesion-to-cord-signal ratio (LCR) was calculated. The ADC value was measured in a quantitative way. Lesions were also graded qualitatively in b800 DWI sequences. There was a significant difference between malignant and benign lesions in terms of DWI grading in b800 images (p
ISSN:2149-2530
2148-7197
2149-2530
2979-9139
DOI:10.5152/TurkThoracJ.2020.19007