Serial block-face scanning electron microscopy: A provocative technique to define 3-dimensional ultrastructure of microvascular thrombosis

Serial block-face scanning electron microscopy: A provocative technique to define 3-dimensional ultrastructure of microvascular thrombosis

•Serial block-face scanning electron microscopy (SBF-SEM) enhances thrombus imaging.•This technique allows for rapid image acquisition and 3-dimensional reconstructions.•SBF-SEM reveals thrombus ultrastructure with high cellular and sub-cellular detail.•This technique has the potential to provide gr...

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Veröffentlicht in:Thrombosis research 2020-12, Vol.196, p.519-522
Hauptverfasser: Courson, Justin A., Hanlon, Samuel D., Bray, Monica A., Lam, Fong W., Burns, Alan R., Rumbaut, Rolando E.
Format: Artikel
Sprache:eng
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Zusammenfassung:•Serial block-face scanning electron microscopy (SBF-SEM) enhances thrombus imaging.•This technique allows for rapid image acquisition and 3-dimensional reconstructions.•SBF-SEM reveals thrombus ultrastructure with high cellular and sub-cellular detail.•This technique has the potential to provide great utility to the field of thrombosis
ISSN:0049-3848
1879-2472
DOI:10.1016/j.thromres.2020.10.008