Effect of Positive End-Expiratory Pressure and Proning on Ventilation and Perfusion in COVID-19 Acute Respiratory Distress Syndrome

Effect of Positive End-Expiratory Pressure and Proning on Ventilation and Perfusion in COVID-19 Acute Respiratory Distress Syndrome

Assessment of lung ventilation and perfusion of coronavirus disease (COVID-19) with acute respiratory distress syndrome (C-ARDS) is still scarce, especially in response to positive end-expiratory pressure (PEEP) and prone positioning. The objective of this study was to describe the physiological eff...

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Veröffentlicht in:American journal of respiratory and critical care medicine 2020-12, Vol.202 (12), p.1713-1717
Hauptverfasser: Perier, François, Tuffet, Samuel, Maraffi, Tommaso, Alcala, Glasiele, Victor, Marcus, Haudebourg, Anne-Fleur, De Prost, Nicolas, Amato, Marcelo, Carteaux, Guillaume, Mekontso Dessap, Armand
Format: Artikel
Sprache:eng
Schlagworte:
Correspondence
COVID-19
COVID-19 - complications
COVID-19 - epidemiology
Female
Humans
Male
Middle Aged
Pandemics
Positive-Pressure Respiration - methods
Respiratory diseases
Respiratory distress syndrome
Respiratory Distress Syndrome - etiology
Respiratory Distress Syndrome - therapy
SARS-CoV-2
Treatment Outcome
Ventilation
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Zusammenfassung:Assessment of lung ventilation and perfusion of coronavirus disease (COVID-19) with acute respiratory distress syndrome (C-ARDS) is still scarce, especially in response to positive end-expiratory pressure (PEEP) and prone positioning. The objective of this study was to describe the physiological effects of PEEP and prone position on respiratory mechanics, ventilation, and pulmonary perfusion in patients with C-ARDS.
ISSN:1073-449X
1535-4970
DOI:10.1164/rccm.202008-3058LE