Oncologic outcomes and patient-reported quality of life in patients with oropharyngeal squamous cell carcinoma treated with definitive transoral robotic surgery versus definitive chemoradiation

Highlights • CRT and definitive TORS offer similar oncologic outcomes in early stage OPSCC. • TORS resulted in improved short and long-term saliva-related QOL compared to CRT. • Use of adjuvant therapy after TORS lead to worse saliva and taste-related QOL. • Use of TORS and N classification were sig...

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Veröffentlicht in:	Oral oncology 2016-10, Vol.61, p.41-46
Hauptverfasser:	Ling, D.C., MD, Chapman, B.V., MD, Kim, J., MD, Choby, G.W., MD, Kabolizadeh, P., MD, PhD, Clump, D.A., MD, PhD, Ferris, R.L., MD, PhD, FACS, Kim, S., MD, Beriwal, S., MD, Heron, D.E., MD, FACRO, FACR, Duvvuri, U., MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Carcinoma, Squamous Cell - pathology Carcinoma, Squamous Cell - surgery Carcinoma, Squamous Cell - therapy Chemoradiotherapy Female Head and neck cancer Hematology, Oncology and Palliative Medicine Humans Male Middle Aged Oropharyngeal cancer Oropharyngeal Neoplasms - pathology Oropharyngeal Neoplasms - surgery Oropharyngeal Neoplasms - therapy Otolaryngology Quality of Life Robotic Surgical Procedures Squamous cell carcinoma Treatment Outcome
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Zusammenfassung:	Highlights • CRT and definitive TORS offer similar oncologic outcomes in early stage OPSCC. • TORS resulted in improved short and long-term saliva-related QOL compared to CRT. • Use of adjuvant therapy after TORS lead to worse saliva and taste-related QOL. • Use of TORS and N classification were significant predictors of saliva-related QOL.
ISSN:	1368-8375 1879-0593
DOI:	10.1016/j.oraloncology.2016.08.004