QOL-24. DIFFERENTIAL IMPACT OF TUMOR LOCATION, LOCAL AND CRANIOSPINAL IRRADIATION ON NEUROPSYCHOLOGICAL LONG-TERM OUTCOME IN CHILDREN WITH MEDULLOBLASTOMA, EPENDYMOMA AND SUPRATENTORIAL PNET: A LONGITUDINAL MULTICENTER OUTCOME ASSESSMENT OF CHILDREN FROM THE HIT-2000 AND HIT-REZ TRIALS

Abstract Neurocognitive deficits are frequent in childhood brain tumor survivors and affect mental intelligence, psychomotor and executive abilities. The differential impact of factors such as disease (location, histology) or treatment (local (LI) vs. craniospinal irradiation (CSI)) on these paramet...

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Veröffentlicht in:	Neuro-oncology (Charlottesville, Va.) Va.), 2020-12, Vol.22 (Supplement_3), p.iii435-iii436
Hauptverfasser:	Ottensmeier, Holger, Schlegel, Paul G, Eyrich, Matthias, Zimolong, Bernhard, Mynarek, Martin, von Hoff, Katja, Frahsek, Stefanie, Schmidt, Rene, Faldum, Andreas, Wolff, Johannes, Fleischhack, Gudrun, Warmuth-Metz, Monika, Krauss, Jürgen, Kortmann, Rolf-Dieter, Galley, Niels, Kühl, Joachim, Rutkowski, Stefan
Format:	Artikel
Sprache:	eng
Schlagworte:	Neuropsychology/Quality of Life
Online-Zugang:	Volltext
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Zusammenfassung:	Abstract Neurocognitive deficits are frequent in childhood brain tumor survivors and affect mental intelligence, psychomotor and executive abilities. The differential impact of factors such as disease (location, histology) or treatment (local (LI) vs. craniospinal irradiation (CSI)) on these parameters is not fully understood. Between 2007–2011 and 2013–2017 300 testings were performed on-site by one neuropsychologist. Of these, 274 tests from n=208 children with medulloblastoma (MB), ependymoma (EP) and supratentorial embryonal tumors (SET)
ISSN:	1522-8517 1523-5866
DOI:	10.1093/neuonc/noaa222.686