Treatment as prevention and cure towards global eradication of hepatitis C virus

Highlights • Treatment as prevention with interferon-free regimens is key to hepatitis C virus eradication. • Making the most effective treatments globally accessible is ethically imperative. • Government/industry investment can reduce societal costs and improve human health. • Eradication depends o...

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Veröffentlicht in:	Trends in microbiology (Regular ed.) 2013-12, Vol.21 (12), p.625-633
Hauptverfasser:	Hagan, Liesl M, Wolpe, Paul Root, Schinazi, Raymond F
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals antiviral agent antiviral agents Antiviral Agents - pharmacology chronic hepatitis C cost effectiveness direct-acting antiviral Disease Eradication drugs educational materials ethics HCV health care workers Hepacivirus - drug effects Hepacivirus - physiology Hepatitis C - drug therapy Hepatitis C - prevention & control Hepatitis C - virology Hepatitis C virus Humans industry interferon-free Internal Medicine prices public health screening stakeholders vaccine development
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Beschreibung
Zusammenfassung:	Highlights • Treatment as prevention with interferon-free regimens is key to hepatitis C virus eradication. • Making the most effective treatments globally accessible is ethically imperative. • Government/industry investment can reduce societal costs and improve human health. • Eradication depends on research towards effective and safe oral pangenotypic regimens.
ISSN:	0966-842X 1878-4380
DOI:	10.1016/j.tim.2013.09.008