Insights on Zika virus envelope gene conservation in American outbreaks

Insights on Zika virus envelope gene conservation in American outbreaks

Phylogenetic studies with Zika virus (ZIKV) have been conducted in Brazil. In this study, we sequenced 8 new sequences of the ZIKV envelope (E) gene from strains of cases from the Paraná and Mato Grosso do Sul states in 2016. A low phylogenetic signal was observed, with more than 40% of unresolved q...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Brazilian journal of microbiology 2020-12, Vol.51 (4), p.1601-1605
Hauptverfasser: Thomazella, Mateus V., Lima Neto, Quirino A., Duarte Junior, Francisco F., Jorge, Fernando A., de Castro Moreira, Déborah, Leal Junior, Amauri D., Presibella, Mayra M., Riediger, Irina N., da Silva, Rafael A., de Carvalho, Isabel Maria V. G., Bertolini, Dennis A.
Format: Artikel
Sprache:eng
Schlagworte:
Bacterial Fungal and Virus Molecular Biology - Short Communication
Biomedical and Life Sciences
Food Microbiology
Life Sciences
Medical Microbiology
Microbial Ecology
Microbial Genetics and Genomics
Microbiology
Mycology
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Phylogenetic studies with Zika virus (ZIKV) have been conducted in Brazil. In this study, we sequenced 8 new sequences of the ZIKV envelope (E) gene from strains of cases from the Paraná and Mato Grosso do Sul states in 2016. A low phylogenetic signal was observed, with more than 40% of unresolved quartets, and the Maximum Likelihood Tree grouped all sequences in the Brazilian branches within the Asian genotype. In addition, a Shannon entropy analysis was conducted, showing a high stability in the E protein through the ZIKV polyprotein. Taken together, these results suggest a high degree of conservation in the ZIKV E gene from the recent American outbreaks.
ISSN:1517-8382
1678-4405
DOI:10.1007/s42770-020-00349-3