$Whole-genome sequencing identifies responders to Pembrolizumab in relapse/refractory natural-killer/T cell lymphoma$

Whole-genome sequencing identifies responders to Pembrolizumab in relapse/refractory natural-killer/T cell lymphoma

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Veröffentlicht in:	Leukemia 2020-12, Vol.34 (12), p.3413-3419
Hauptverfasser:	Lim, Jing Quan, Huang, Dachuan, Tang, Tiffany, Tan, Daryl, Laurensia, Yurike, Peng, Rou-Jun, Wong, Esther Kam Yin, Cheah, Daryl Ming Zhe, Chia, Burton Kuan Hui, Iqbal, Jabed, Grigoropoulos, Nicholas Francis, Nairismägi, Maarja-Liisa, Ng, Cedric Chuan Young, Rajasegaran, Vikneswari, Hong, Huangming, Kim, Seok Jin, Cho, Junhun, Tse, Eric, Mow, Benjamin, Cai, Qi-Chun, Poon, Li-Mei, Cai, Qing-qing, Tan, Jing, Chan, Jason Yongsheng, Lim, Johnathan Xiande, Goh, Yeow Tee, Phipps, Colin, Rötzschke, Olaf, Cheng, Chee Leong, Ha, Jeslin Chian Hung, Khoo, Lay Poh, Loh, Yvonne Su Ming, Au-Yeung, Rex, Chan, Thomas Sau-Yan, Kwong, Yok-Lam, Hwang, William, Kim, Won Seog, Bei, Jin-Xin, Lin, Tongyu, Ong, Choon Kiat, Lim, Soon Thye
Format:	Artikel
Sprache:	eng
Schlagworte:	45/23 45/47 631/67/69 692/308/575 82/51 Adult Aged Antibodies, Monoclonal, Humanized - therapeutic use Cancer Research Care and treatment Critical Care Medicine Development and progression Enzyme inhibitors Female Gene sequencing Genetic aspects Genome-wide association studies Genomes Hematology Humans Immunotherapy Intensive Internal Medicine Killer Cells, Natural - drug effects Letter Lymphocytes Lymphocytes T Lymphoma Lymphoma, T-Cell - drug therapy Lymphoma, T-Cell - genetics Lymphomas Male Medicine Medicine & Public Health Methods Middle Aged Monoclonal antibodies Neoplasm Recurrence, Local - drug therapy Neoplasm Recurrence, Local - genetics Oncology Patient outcomes Pembrolizumab T-cell lymphoma Targeted cancer therapy Whole genome sequencing Whole Genome Sequencing - methods
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ISSN:	0887-6924 1476-5551
DOI:	10.1038/s41375-020-1000-0