Oral iron supplementation with ferric maltol in patients with pulmonary hypertension
Iron deficiency is common in patients with pulmonary hypertension [1, 2]. The underlying pathomechanisms are complex and include impaired iron absorption, elevated hepcidin levels, augmented gastrointestinal loss and reduced availability from the reticuloendothelial system [1, 3, 4]. In patients wit...
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Veröffentlicht in: | The European respiratory journal 2020-11, Vol.56 (5), p.2000616 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Iron deficiency is common in patients with pulmonary hypertension [1, 2]. The underlying pathomechanisms are complex and include impaired iron absorption, elevated hepcidin levels, augmented gastrointestinal loss and reduced availability from the reticuloendothelial system [1, 3, 4]. In patients with pulmonary hypertension, iron deficiency is associated with aggravated symptoms and an increased mortality risk [3, 5].
Oral ferric maltol was well tolerated and effective in patients with pulmonary hypertension and iron deficiency anaemia. Restoration of iron stores corrected anaemia and resulted in improved right ventricular function and exercise tolerance
https://bit.ly/2zMwvxc |
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ISSN: | 0903-1936 1399-3003 |
DOI: | 10.1183/13993003.00616-2020 |