Pulmonary embolism in COVID-19 patients: prevalence, predictors and clinical outcome

The incidence, characteristics, and prognosis of pulmonary embolism (PE) in Coronavirus disease 2019 (COVID-19) have been poorly investigated. We aimed to investigate the prevalence and the correlates with the occurrence of PE as well as the association between PE and the risk of mortality in COVID-...

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Veröffentlicht in:Thrombosis research 2021-02, Vol.198, p.34-39
Hauptverfasser: Scudiero, Fernando, Silverio, Angelo, Di Maio, Marco, Russo, Vincenzo, Citro, Rodolfo, Personeni, Davide, Cafro, Andrea, D'Andrea, Antonello, Attena, Emilio, Pezzullo, Salvatore, Canonico, Mario Enrico, Galasso, Gennaro, Pitì, Antonino, Parodi, Guido
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Sprache:eng
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Zusammenfassung:The incidence, characteristics, and prognosis of pulmonary embolism (PE) in Coronavirus disease 2019 (COVID-19) have been poorly investigated. We aimed to investigate the prevalence and the correlates with the occurrence of PE as well as the association between PE and the risk of mortality in COVID-19. Retrospective multicenter study on consecutive COVID-19 patients hospitalized at 7 Italian Hospitals. At admission, all patients underwent medical history, laboratory and echocardiographic evaluation. The study population consisted of 224 patients (mean age 69 ± 14, male sex 62%); PE was diagnosed in 32 cases (14%). Patients with PE were hospitalized after a longer time since symptoms onset (7 IQR 3–11 days, 3 IQR 1–6 days; p = 0.001) and showed higher D-dimers level (1819 IQR 568–5017 ng/ml vs 555 IQR 13–1530 ng/ml; p 
ISSN:0049-3848
1879-2472
1879-2472
DOI:10.1016/j.thromres.2020.11.017