Complexation with Random Methyl-β-Cyclodextrin and (2-Hydroxypropyl)-β-Cyclodextrin Promotes Chrysin Effect and Potential for Liver Fibrosis Therapy

Liver fibrosis results from chronic liver injury and is characterized by the accumulation of extracellular matrix in excess driven by hepatic stellate cells (HSCs) activation. Chrysin (CHR) is a natural flavonoid that is limited by its low solubility to exert its anti-inflammatory, antioxidant and a...

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Veröffentlicht in:	Materials 2020-11, Vol.13 (21), p.5003
Hauptverfasser:	Ignat, Simona-Rebeca, Dinescu, Sorina, Váradi, Judit, Fenyvesi, Ferenc, Nguyen, Thi Le Phuong, Ciceu, Alina, Hermenean, Anca, Costache, Marieta
Format:	Artikel
Sprache:	eng
Schlagworte:	Antioxidants Binding sites Biocompatibility Cell culture Cyclodextrins Fibrosis Glutathione Growth factors Liver Liver cancer Microscopy Peroxidase Superoxide dismutase Toxicity testing Tumor necrosis factor-TNF
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