Sex-related differences in risk factors, outcome, and quality of life in patients with permanent atrial fibrillation: results from the RACE II study

Sex-related differences in risk factors, outcome, and quality of life in patients with permanent atrial fibrillation: results from the RACE II study

Abstract Aims Atrial fibrillation (AF) risk factors translate into disease progression. Whether this affects women and men differently is unclear. We aimed to investigate sex differences in risk factors, outcome, and quality of life (QoL) in permanent AF patients. Methods and results The Rate Contro...

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Veröffentlicht in:Europace (London, England) England), 2020-11, Vol.22 (11), p.1619-1627
Hauptverfasser: Kloosterman, Mariëlle, Crijns, Harry J G M, Mulder, Bart A, Groenveld, Hessel F, Van Veldhuisen, Dirk J, Rienstra, Michiel, Van Gelder, Isabelle C
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Sprache:eng
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Clinical Research
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Zusammenfassung:Abstract Aims Atrial fibrillation (AF) risk factors translate into disease progression. Whether this affects women and men differently is unclear. We aimed to investigate sex differences in risk factors, outcome, and quality of life (QoL) in permanent AF patients. Methods and results The Rate Control Efficacy in Permanent Atrial Fibrillation (RACE II) randomized 614 patients, 211 women and 403 men, to lenient or strict rate control. In this post hoc analysis risk factors, cardiovascular events during 3-year follow-up (cardiovascular death, heart failure hospitalization, stroke, systemic embolism, bleeding, and life-threatening arrhythmic events), outcome parameters, and QoL were compared between the sexes. Women were older (71 ± 7 vs. 66 ± 8 years, P 
ISSN:1099-5129
1532-2092
DOI:10.1093/europace/euz300