B-lymphoblastic leukemia arising in a patient with chronic neutrophilic leukemia
•We report the first identified case of chronic neutrophilic leukemia with transformation to B-lymphoblastic leukemia.•Genetic alterations involving CSF3R, ASXL1, SRSF2, and RUNX1 contributed to the unusual progression and may drive B-cell leukemogenesis.
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| Veröffentlicht in: | Blood advances 2020-11, Vol.4 (21), p.5389-5392 |
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| container_end_page | 5392 |
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| container_issue | 21 |
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| container_title | Blood advances |
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| creator | Boddy, Craig S. Tan, Brent T. Aoki, Joseph |
| description | •We report the first identified case of chronic neutrophilic leukemia with transformation to B-lymphoblastic leukemia.•Genetic alterations involving CSF3R, ASXL1, SRSF2, and RUNX1 contributed to the unusual progression and may drive B-cell leukemogenesis. |
| doi_str_mv | 10.1182/bloodadvances.2020003109 |
| format | Article |
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| ispartof | Blood advances, 2020-11, Vol.4 (21), p.5389-5392 |
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| language | eng |
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| source | MEDLINE; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Exceptional Case Report Humans Leukemia, B-Cell Leukemia, Neutrophilic, Chronic - diagnosis Leukemia, Neutrophilic, Chronic - genetics Precursor Cell Lymphoblastic Leukemia-Lymphoma |
| title | B-lymphoblastic leukemia arising in a patient with chronic neutrophilic leukemia |
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