Engineered trimeric ACE2 binds viral spike protein and locks it in “Three-up” conformation to potently inhibit SARS-CoV-2 infection

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Bibliographische Detailangaben
Veröffentlicht in:	Cell research 2021-01, Vol.31 (1), p.98-100
Hauptverfasser:	Guo, Liang, Bi, Wenwen, Wang, Xinling, Xu, Wei, Yan, Renhong, Zhang, Yuanyuan, Zhao, Kai, Li, Yaning, Zhang, Mingfeng, Cai, Xia, Jiang, Shibo, Xie, Youhua, Zhou, Qiang, Lu, Lu, Dang, Bobo
Format:	Artikel
Sprache:	eng
Schlagworte:	101/28 631/337 631/535/1258/1259 82/103 82/16 82/80 82/83 ACE2 Angiotensin-converting enzyme 2 Angiotensin-Converting Enzyme 2 - chemistry Angiotensin-Converting Enzyme 2 - pharmacology Biomedical and Life Sciences Cell Biology COVID-19 - metabolism COVID-19 Drug Treatment Humans Letter to the Editor Life Sciences Mutation, Missense Protein Binding Protein Engineering Protein Multimerization SARS-CoV-2 - chemistry SARS-CoV-2 - metabolism Severe acute respiratory syndrome coronavirus 2 Spike protein Viral diseases
Online-Zugang:	Volltext
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